NovaCardia Presents Positive Results Of Two Phase II Trials In Late-Breaking Trials Session At Heart Failure 2006 Congress

These facts, also label in a dealings published online closing week (May 30, 2007) in the medical chronicle The Lancet, be further testimony that the ischemic cardiovascular refuge of Avandia be comparable to the supreme universally previously to the point kind 2 diabetes coverage - in deposit of evidence in long-term prospective trial, such as ADOPT and DREAM. The findings fighting touching a conjecture generate with the just this minute published meta-analysis in the New England Journal of Medicine that raise exactness in connection with ischemic risk with Avandia.

"We be amazingly impelled with the preliminary study findings that suggest that the incorporation of KW-3902 to typical diuretic therapy may save renal function while enhancing diuresis," mention Howard Dittrich, M.D., Chief Medical Officer of NovaCardia. "Since crumbling of renal function skip on time and again in CHF patients and be predictive of increased mortality and length of sickbay control, these findings suggest KW-3902 could be an prominent addition to the physiotherapy of acutely decompensated heart failure patients." Results from a randomized, double-blind, placebo-controlled dose escalation exploratory study be also presented in place of part of the pack of the Late-Breaking Trials Session. The study examined 34 patients refractory to diuretics. KW- 3902 resulted in increased hourly urine rumpus, with relatively hermetic kidney function, over a nine hour period compare to placebo. These findings suggest that KW-3902 may prove useful in facilitate diuresis in patients refractory to conformist.

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